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Gene APC
Variant D1022G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC D1022G lies within the beta-catenin binding domain of the Apc protein (PMID: 14672538). D1022G has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC D1022G

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Transcript NM_000038.6
gDNA chr5:g.112838659A>G
cDNA c.3065A>G
Protein p.D1022G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001127510 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112838659A>G c.3065A>G p.D1022G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References