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Gene | TP53 |
Variant | R213G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 R213G lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). R213G has been identified in sequencing studies (PMID: 28744014, PMID: 38643353, PMID: 31590326), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon6 TP53 R213G |
Transcript | NM_000546.6 |
gDNA | chr17:g.7674894G>C |
cDNA | c.637C>G |
Protein | p.R213G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |