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Gene DNMT3A
Variant R19W
Impact List missense
Protein Effect unknown
Gene Variant Descriptions DNMT3A R19W does not lie within any known functional domains of the Dnmt3a protein (UniProt.org). R19W has been identified in the scientific literature (PMID: 24793135, PMID: 23305405), but has not been biochemically characterized and therefore, its effect on Dnmt3a protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

DNMT3A mutant DNMT3A R19W

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Transcript NM_022552.5
gDNA chr2:g.25313930G>A
cDNA c.55C>T
Protein p.R19W
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011532664.2 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_001320892.2 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_011532664 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_022552.5 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175629.2 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_022552.4 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_005264175 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_011532664.3 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_017003526.2 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175630.1 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_005264175.6 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_047443593.1 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175630 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_017003526.1 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_001320892 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175629 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175629.2 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_005264175.5 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_022552 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_001320892.1 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
NM_175630.1 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38
XM_017003526 chr2:g.25313930G>A c.55C>T p.R19W RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References