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Gene APC
Variant S590N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC S590N lies within ARM repeat 3 of the Apc protein (UniProt.org). S590N has been identified in sequencing studies (PMID: 28002797), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC S590N

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Transcript NM_000038.6
gDNA chr5:g.112834976G>A
cDNA c.1769G>A
Protein p.S590N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407454.1 chr5:g.112837612G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001407456.1 chr5:g.112837612G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001127510 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001407470.1 chr5:g.112838211_112838212delTCinsAA c.1768_1769delTCinsAA p.S590N RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001407455.1 chr5:g.112837612G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001354906.2 chr5:g.112838211_112838212delTCinsAA c.1768_1769delTCinsAA p.S590N RefSeq GRCh38/hg38
NM_001407457.1 chr5:g.112837612G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_000038 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38
NM_001354906.1 chr5:g.112838211_112838212delTCinsAA c.1768_1769delTCinsAA p.S590N RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112834976G>A c.1769G>A p.S590N RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
APC S590N unknown