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Gene RAD51C
Variant G264V
Impact List missense
Protein Effect no effect
Gene Variant Descriptions RAD51C G264V does not lie within any known functional domains of the Rad51c protein (UniProt.org). G264V demonstrates rescue of mitomycin C hypersensitivity and Rad51 foci formation similar to wild-type Rad51c in culture (PMID: 20400964).
Associated Drug Resistance
Category Variants Paths

RAD51C mutant RAD51C G264V

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Transcript NM_058216.3
gDNA chr17:g.58709944G>T
cDNA c.791G>T
Protein p.G264V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006722002.4 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
XM_006722001.4 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
XM_006722001 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
XM_006722001.5 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
XM_006722002 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
NM_058216.2 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
NM_058216 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
NM_058216.3 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38
XM_006722002.5 chr17:g.58709944G>T c.791G>T p.G264V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References