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Gene FGFR1
Variant P772L
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR1 P772L lies within the cytoplasmic domain of the Fgfr1 protein (UniProt.org). P772L has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Fgfr1 in cultured cells (PMID: 29533785), and therefore, is predicted to have no effect on Fgfr1 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 P772L

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Transcript NM_023110.3
gDNA chr8:g.38413782G>A
cDNA c.2315C>T
Protein p.P772L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001174067.2 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544445.2 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_001174067.1 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544447 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_017013223 chr8:g.38412561G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_001354369.1 chr8:g.38412561G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_001354369.2 chr8:g.38412561G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544445.3 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_023110 chr8:g.38413782G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_001174067 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544444 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38413782G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544447.2 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38413782G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544444.1 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_047421569.1 chr8:g.38412561G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544447.3 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544445 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38
XM_011544444.2 chr8:g.38413988G>A c.2315C>T p.P772L RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR1 P772L no effect - predicted