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Gene | FGFR1 |
Variant | T370A |
Impact List | missense |
Protein Effect | no effect - predicted |
Gene Variant Descriptions | FGFR1 T370A lies within the extracellular domain of the Fgfr1 protein (UniProt.org). T370A has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Fgfr1 in cultured cells (PMID: 29533785), and therefore, is predicted to have no effect on Fgfr1 protein function. |
Associated Drug Resistance | |
Category Variants Paths |
FGFR1 mutant FGFR1 T370A |
Transcript | NM_023110.3 |
gDNA | chr8:g.38419709T>C |
cDNA | c.1108A>G |
Protein | p.T370A |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |