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FGFR1 Y307N - Gene Variant Detail

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Gene FGFR1
Variant Y307N
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR1 Y307N lies within Ig-like C2-type domain 3 of the Fgfr1 protein (UniProt.org). Y307N has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Fgfr1 in cultured cells (PMID: 29533785), and therefore, is predicted to have no effect on Fgfr1 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 Y307N

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Transcript NM_023110.3
gDNA chr8:g.38424526A>T
cDNA c.919T>A
Protein p.Y307N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001174063.1 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716303 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
NM_001174063.2 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_017013222 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
NM_001174063 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_017013222.2 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_047421570.1 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_017013221 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
NM_023110 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38
XM_006716304 chr8:g.38424526A>T c.919T>A p.Y307N RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries