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Gene FGFR3
Variant D762H
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR3 D762H lies within the cytoplasmic domain of the Fgfr3 protein (UniProt.org). D762H results in similar cell proliferation and viability levels as wild-type Fgfr3 in culture (PMID: 29533785), and therefore, is predicted to have no effect on Fgfr3 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 D762H

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Transcript NM_000142.5
gDNA chr4:g.1807125G>C
cDNA c.2284G>C
Protein p.D762H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006713868.2 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_006713868 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_006713868.1 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1807125G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_006713869.2 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_047449824.1 chr4:g.1807125G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_006713869.1 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
NM_000142 chr4:g.1807125G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_006713869 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
NM_000142.5 chr4:g.1807125G>C c.2284G>C p.D762H RefSeq GRCh38/hg38
XM_047449820.1 chr4:g.1806932G>C c.2284G>C p.D762H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR3 D762H no effect - predicted