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Gene | PIK3CA |
Variant | P298S |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA P298S does not lie within any known functional domains of the Pik3ca protein (UniProt.org). P298S has not been characterized in the scientific literature and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA exon5 PIK3CA P298S |
Transcript | NM_006218.4 |
gDNA | chr3:g.179203622C>T |
cDNA | c.892C>T |
Protein | p.P298S |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_006218.3 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
NM_006218 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
XM_011512894 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
NM_006218.4 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
XM_006713658 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
XM_006713658.4 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
XM_011512894.2 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
XM_006713658.5 | chr3:g.179203622C>T | c.892C>T | p.P298S | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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