HRAS Q61N
Gene Variant Detail

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Gene HRAS
Variant Q61N
Impact List missense
Protein Effect loss of function
Gene Variant Descriptions HRAS Q61N does not lie within any known functional domains of the Hras protein (UniProt.org). Q61N confers a loss of function to Hras protein as indicated by decreased Hras GTPase activity in an in vitro assay and transformation of cells in culture (PMID: 3510078).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS act mut HRAS Q61N

HRAS mutant HRAS Q61X HRAS Q61N

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Transcript NM_005343.4
gDNA chr11:g.533873_533875delCAGinsAAC
cDNA c.181_183delCAGinsAAC
Protein p.Q61N
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.