HRAS Q61I
Gene Variant Detail

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Gene HRAS
Variant Q61I
Impact List missense
Protein Effect loss of function - predicted
Gene Variant Descriptions HRAS Q61I does not lie within any known functional domains of the Hras protein (UniProt.org). Q61I is transforming in culture (PMID: 3510078) and therefore, is predicted to lead to a loss of Hras protein function and activation of downstream signaling.
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS act mut HRAS Q61I

HRAS mutant HRAS Q61X HRAS Q61I

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Transcript NM_005343.4
gDNA chr11:g.533873_533875delCAGinsATC
cDNA c.181_183delCAGinsATC
Protein p.Q61I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_176795.5 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_001130442 chr11:g.533873_533875delCTGinsGAT c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_176795 chr11:g.533873_533875delCTGinsGAT c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_005343 chr11:g.533873_533875delCTGinsGAT c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.533873_533875delCAGinsATC c.181_183delCAGinsATC p.Q61I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries