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HRAS Q61M - Gene Variant Detail

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Gene HRAS
Variant Q61M
Impact List missense
Protein Effect loss of function
Gene Variant Descriptions HRAS Q61M does not lie within any known functional domains of the Hras protein (UniProt.org). Q61M results in decreased Hras GTPase activity and leads to transformation of cells in culture (PMID: 3510078).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS act mut HRAS Q61M

HRAS mutant HRAS Q61X HRAS Q61M

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Transcript NM_005343.4
gDNA chr11:g.533874_533875delCAinsAT
cDNA c.181_182delCAinsAT
Protein p.Q61M
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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