KDR S925F
Gene Variant Detail

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Gene KDR
Variant S925F
Impact List missense
Protein Effect gain of function - predicted
Gene Variant Descriptions KDR (VEGFR2) S925F lies within the protein kinase domain of the Kdr (Vegfr2) protein (UniProt.org). S925F results in tumor formation in mouse models (PMID: 29588308), and therefore, is predicted to lead to a gain of Kdr (Vegfr2) protein function.
Associated Drug Resistance
Category Variants Paths

KDR mutant KDR act mut KDR S925F

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Transcript NM_002253.4
gDNA chr4:g.55095620G>A
cDNA c.2774C>T
Protein p.S925F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002253.4 chr4:g.55095620G>A c.2774C>T p.S925F RefSeq GRCh38/hg38
NM_002253 chr4:g.55095620G>A c.2774C>T p.S925F RefSeq GRCh38/hg38
NM_002253.3 chr4:g.55095620G>A c.2774C>T p.S925F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries