ERBB3 K329T
Gene Variant Detail

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Gene ERBB3
Variant K329T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions ERBB3 (HER3) K329T lies within the extracellular domain of the Erbb3 (Her3) protein (PMID: 29963236). K329T results in cell proliferation levels similar to wild-type Erbb3 (Her3) in culture (PMID: 29963236), and therefore, is predicted to have no effect on Erbb3 (Her3) protein function.
Associated Drug Resistance
Category Variants Paths

ERBB3 mutant ERBB3 K329T

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Transcript NM_001982.4
gDNA chr12:g.56088654A>C
cDNA c.986A>C
Protein p.K329T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001982 chr12:g.56088654A>C c.986A>C p.K329T RefSeq GRCh38/hg38
NM_001982.4 chr12:g.56088654A>C c.986A>C p.K329T RefSeq GRCh38/hg38
NM_001982.3 chr12:g.56088654A>C c.986A>C p.K329T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
ERBB3 K329T no effect - predicted