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Gene APC
Variant T1160K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC T1160K lies within the beta-catenin binding domain of the Apc protein (PMID: 14672538). T1160K has been identified in the scientific literature (PMID: 29212164), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC T1160K

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Transcript NM_000038.6
gDNA chr5:g.112839073C>A
cDNA c.3479C>A
Protein p.T1160K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510.2 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001407459.1 chr5:g.112839376_112839377delCTinsAG c.3479_3480delCTinsAG p.T1160K RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001407458.1 chr5:g.112839376_112839377delCTinsAG c.3479_3480delCTinsAG p.T1160K RefSeq GRCh38/hg38
NM_001354898.2 chr5:g.112839148C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001354903.1 chr5:g.112839376_112839377delCTinsAG c.3479_3480delCTinsAG p.T1160K RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001354898.1 chr5:g.112839148C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001127510 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001354903.2 chr5:g.112839376_112839377delCTinsAG c.3479_3480delCTinsAG p.T1160K RefSeq GRCh38/hg38
NM_001407460.1 chr5:g.112839376_112839377delCTinsAG c.3479_3480delCTinsAG p.T1160K RefSeq GRCh38/hg38
NM_000038 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839073C>A c.3479C>A p.T1160K RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References