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Gene IDH1
Variant R100X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions IDH1 R100X indicates any Idh1 missense mutation that results in replacement of the arginine (R) at amino acid 100 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

IDH1 mutant IDH1 R100X

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Transcript NM_005896.4
gDNA chr2:g.208248483_208248485
cDNA c.298_300
Protein p.R100
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001282387.1 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38
NM_005896.4 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38
NM_001282386.1 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38
NM_001282386.1 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38
NM_001282387.1 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38
NM_005896.3 chr2:g.208248483_208248485 c.298_300 p.R100 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03914742 Phase Ib/II Pamiparib + Temozolomide BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations Completed USA 0
NCT04493164 Phase II CPX-351 + Ivosidenib Ivosidenib CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome Recruiting USA 0