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Gene FGFR1
Variant A626V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 A626V lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). A626V has been identified in sequencing studies (PMID: 29698444), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 A626V

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Transcript NM_023110.3
gDNA chr8:g.38414879G>A
cDNA c.1877C>T
Protein p.A626V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716303.3 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
NM_023110 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_017013221 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_006716304 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_006716303 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38414879G>A c.1877C>T p.A626V RefSeq GRCh38/hg38

Filtering

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References