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Gene JAK2
Variant L941F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK2 L941F lies within protein kinase domain 2 of the Jak2 protein (UniProt.org). L941F has been identified in sequencing studies (PMID: 31742675, PMID: 30811597, PMID: 27997549), but has not been biochemically characterized and therefore, its effect on Jak2 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

JAK2 mutant JAK2 L941F

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Transcript NM_004972.4
gDNA chr9:g.5090505C>T
cDNA c.2821C>T
Protein p.L941F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001322196 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322196.1 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_004972.4 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322194 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322194.1 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322195.1 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322195.2 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322195 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322196.2 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_004972.3 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_001322194.2 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38
NM_004972 chr9:g.5090505C>T c.2821C>T p.L941F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
JAK2 L941F unknown