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Gene JAK2
Variant S15F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK2 S15F lies within the cytokine/interferon/growth hormone receptors-interacting region of the Jak2 protein (UniProt.org). S15F has been identified in the scientific literature (PMID: 30811597, PMID: 28561041), but has not been biochemically characterized and therefore, its effect on Jak2 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

JAK2 mutant JAK2 S15F

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Transcript NM_004972.4
gDNA chr9:g.5022031C>T
cDNA c.44C>T
Protein p.S15F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001322195 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322196 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322196.2 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322194.1 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322196.1 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_004972 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_004972.3 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322194.2 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322194 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322195.1 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_001322195.2 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38
NM_004972.4 chr9:g.5022031C>T c.44C>T p.S15F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References