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| Gene | HRAS |
| Variant | inact mut |
| Impact List | unknown |
| Protein Effect | loss of function |
| Gene Variant Descriptions | HRAS inact mut indicates that the variant results in failure to activate HRAS downstream signaling. However, the specific amino acid change has not been identified. |
| Associated Drug Resistance | |
| Category Variants Paths |
HRAS mutant HRAS inact mut |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| HRAS inact mut | loss of function | MEK inhibitor (Pan) MEK1 Inhibitor MEK2 Inhibitor PI3K Inhibitor (Pan) PIK3CA inhibitor PIK3CB inhibitor PIK3CD inhibitor PIK3CG inhibitor RAS Inhibitor (Pan) |