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Gene | FBXW7 |
Variant | A503T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 A503T lies within WD repeat 4 of the Fbxw7 protein (UniProt.org). A503T has been identified in sequencing studies (PMID: 25148578), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 A503T |
Transcript | NM_033632.3 |
gDNA | chr4:g.152326143C>T |
cDNA | c.1507G>A |
Protein | p.A503T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |