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Gene | FBXW7 |
Variant | V265I |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 V265I does not lie within any known functional domains of the Fbxw7 protein (UniProt.org). V265I has been identified in sequencing studies (PMID: 21282377), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Apr 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 V265I |
Transcript | NM_033632.3 |
gDNA | chr4:g.152337870C>T |
cDNA | c.793G>A |
Protein | p.V265I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |