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| Gene | RAD54L |
| Variant | del |
| Impact List | deletion |
| Protein Effect | loss of function |
| Gene Variant Descriptions | RAD54L del indicates a deletion of the RAD54L gene. |
| Associated Drug Resistance | |
| Category Variants Paths |
RAD54L mutant RAD54L inact mut RAD54L del |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04779151 | Phase II | Dostarlimab-gxly + Niraparib | Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab (NIRADO) | Terminated | FRA | 0 |
| NCT04276376 | Phase II | Atezolizumab + Rucaparib | Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors (ARIANES) | Terminated | FRA | 0 |
| NCT03840967 | Phase II | Niraparib | A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma | Terminated | USA | 0 |