PIK3CA E542X
Gene Variant Detail

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Gene PIK3CA
Variant E542X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA E542X indicates any PIK3CA missense mutation that results in the replacement of the glutamic acid (E) at amino acid 542 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA exon10 PIK3CA E542X

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Transcript NM_006218.4
gDNA chr3:g.179218294_179218296
cDNA c.1624_1626
Protein p.E542
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011512894.2 chr3:g.179218294_179218296 c.1624_1626 p.E542 RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179218294_179218296 c.1624_1626 p.E542 RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179218294_179218296 c.1624_1626 p.E542 RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179218294_179218296 c.1624_1626 p.E542 RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179218294_179218296 c.1624_1626 p.E542 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References