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Gene CSF3R
Variant E831*
Impact List nonsense
Protein Effect no effect
Gene Variant Descriptions CSF3R E831* results in a premature truncation of the Csf3r protein at amino acid 831 of 836 (UniProt.org). E831* results in cell surface Csf3r expression, Stat5 activation, and receptor degradation similar to wild-type, and is not transforming in cell culture (PMID: 28439110), and therefore, has no effect on Csf3r protein function.
Associated Drug Resistance
Category Variants Paths

CSF3R mutant CSF3R E831*

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Transcript NM_000760.4
gDNA chr1:g.36466377C>A
cDNA c.2491G>T
Protein p.E831*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000760 chr1:g.36466377C>A c.2491G>T p.E831* RefSeq GRCh38/hg38
NM_000760.4 chr1:g.36466377C>A c.2491G>T p.E831* RefSeq GRCh38/hg38
NM_000760.3 chr1:g.36466377C>A c.2491G>T p.E831* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References