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Gene | FBXW7 |
Variant | W606* |
Impact List | nonsense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 W606* results in a premature truncation of the Fbxw7 protein at amino acid 606 of 707 (UniProt.org). W606* has been identified in the scientific literature (PMID: 27870570), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Apr 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 W606* |
Transcript | NM_033632.3 |
gDNA | chr4:g.152324222C>T |
cDNA | c.1817G>A |
Protein | p.W606* |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |