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Gene FGFR1
Variant V444A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 V444A lies within the cytoplasmic domain of the Fgfr1 protein (UniProt.org). V444A has been identified in sequencing studies (PMID: 31328403), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 V444A

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Transcript NM_023110.3
gDNA chr8:g.38418327A>G
cDNA c.1331T>C
Protein p.V444A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716303.3 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_006716304 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_017013221 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
NM_023110 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_006716303 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38418327A>G c.1331T>C p.V444A RefSeq GRCh38/hg38

Filtering

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References