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Gene | NRAS |
Variant | A11T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | NRAS A11T lies within a GTP-binding region of the Nras protein (UniProt.org). A11T has been identified in the scientific literature (PMID: 2183888), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, May 2025). |
Associated Drug Resistance | |
Category Variants Paths |
NRAS mutant NRAS exon2 NRAS A11T |
Transcript | NM_002524.5 |
gDNA | chr1:g.114716130C>T |
cDNA | c.31G>A |
Protein | p.A11T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |