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| Gene | NRAS |
| Variant | A11T |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | NRAS A11T lies within a GTP-binding region of the Nras protein (UniProt.org). A11T has been identified in the scientific literature (PMID: 2183888), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, Nov 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
NRAS mutant NRAS exon2 NRAS A11T |
| Transcript | NM_002524.5 |
| gDNA | chr1:g.114716130C>T |
| cDNA | c.31G>A |
| Protein | p.A11T |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_002524.4 | chr1:g.114716130C>T | c.31G>A | p.A11T | RefSeq | GRCh38/hg38 |
| NM_002524.5 | chr1:g.114716130C>T | c.31G>A | p.A11T | RefSeq | GRCh38/hg38 |
| NM_002524 | chr1:g.114716130C>T | c.31G>A | p.A11T | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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