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Gene | PIK3CA |
Variant | exon21 |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA exon 21 indicates an unspecified mutation has occurred in exon 21 (corresponding to amino acids 979 to 1068) of the PIK3CA gene. PIK3CA exon 21 is sometimes reported as exon 20, when only coding exons are considered in numbering. |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA exon21 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT05625087 | Phase II | Fulvestrant + Ribociclib Alpelisib + Fulvestrant | Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib (SAFIR 03) | Recruiting | FRA | 0 |