NRAS G13S
Gene Variant Detail

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Gene NRAS
Variant G13S
Impact List missense
Protein Effect gain of function - predicted
Gene Variant Descriptions NRAS G13S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13S has not been characterized, but can be predicted to lead to a gain of Nras protein function and activation of downstream signaling based on the effects of HRAS G13S (PMID: 8430333).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS act mut NRAS G13S

NRAS mutant NRAS exon2 NRAS G13X NRAS G13S

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Transcript NM_002524.5
gDNA chr1:g.114716124C>T
cDNA c.37G>A
Protein p.G13S
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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