TET2 C1396R
Gene Variant Detail

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Gene TET2
Variant C1396R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TET2 C1396R lies within the catalytic domain of the Tet2 protein (PMID: 24315485). C1396R has been identified in sequencing studies (PMID: 27908881), but has not been biochemically characterized and therefore, its effect on Tet2 protein function is unknown (PubMed, Jun 2025).
Associated Drug Resistance
Category Variants Paths

TET2 mutant TET2 C1396R

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Transcript NM_001127208.3
gDNA chr4:g.105272567T>C
cDNA c.4186T>C
Protein p.C1396R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_024454102.2 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
NM_001127208.2 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_005263082.3 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_024454103.1 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
NM_001127208.3 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_005263082.4 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_005263082 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_024454103.2 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
NM_001127208 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38
XM_024454102.1 chr4:g.105272567T>C c.4186T>C p.C1396R RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References