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Gene FGFR1
Variant G610D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 G610D lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). G610D has been identified in the scientific literature (PMID: 36462464, PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 G610D

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Transcript NM_023110.3
gDNA chr8:g.38415895C>T
cDNA c.1829G>A
Protein p.G610D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_023110 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716304 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
NM_001354368.2 chr8:g.38414230C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_017013228 chr8:g.38414230C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
NM_001354368.1 chr8:g.38414230C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_047421574.1 chr8:g.38414230C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716303 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_017013221 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38415895C>T c.1829G>A p.G610D RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References