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Gene FGFR3
Variant Y373H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR3 Y373H lies within the extracellular domain of the Fgfr3 protein (UniProt.org). Y373H has been identified in the scientific literature (PMID: 34160364), but has not been biochemically characterized, and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 Y373H

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Transcript NM_000142.5
gDNA chr4:g.1804371T>C
cDNA c.1117T>C
Protein p.Y373H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011513422.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_011513420.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_006713873 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_001354810.2 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_006713873.2 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_011513422.2 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_000142 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_001354809.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_047449822.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_047449824.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_011513420 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_006713872 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_047449823.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_011513422 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_011513420.2 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
XM_006713873.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_001354809.2 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_000142.5 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38
NM_001354810.1 chr4:g.1804371T>C c.1117T>C p.Y373H RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References