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Gene FGFR2
Variant M538R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 M538R lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). M538R has not been characterized in the scientific literature and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 M538R

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Transcript NM_000141.5
gDNA chr10:g.121498554A>C
cDNA c.1613T>G
Protein p.M538R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006717710.4 chr10:g.121500834A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001144913 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_000141 chr10:g.121498554A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001320658 chr10:g.121498548A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121498554A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121498548A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
XM_006717710.5 chr10:g.121500834A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121498548A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
XM_006717710 chr10:g.121500834A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_022970 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121498557A>C c.1613T>G p.M538R RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121498554A>C c.1613T>G p.M538R RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References