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Gene RAD51B
Variant Q371*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions RAD51B Q371* results in a premature truncation of the Rad51b protein at amino acid 371 of 384 (UniProt.org). Q371* has been identified in sequencing studies (PMID: 30205045, PMID: 36277904), but has not been biochemically characterized and therefore, its effect on Rad51b protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

RAD51B mutant RAD51B Q371*

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Transcript NM_133509.5
gDNA chr14:g.68594559C>T
cDNA c.1111C>T
Protein p.Q371*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_133509 chr14:g.68594559C>T c.1111C>T p.Q371* RefSeq GRCh38/hg38
NM_133509.3 chr14:g.68594559C>T c.1111C>T p.Q371* RefSeq GRCh38/hg38
NM_133509.5 chr14:g.68594559C>T c.1111C>T p.Q371* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References