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Gene | CDKN2A |
Variant | L62_E69del |
Impact List | deletion |
Protein Effect | unknown |
Gene Variant Descriptions | CDKN2A L62_E69del results in the deletion of eight amino acids in ANK repeat 2 of the Cdkn2a protein from amino acids 62 to 69 (UniProt.org). L62_E69del has not been characterized in the scientific literature and therefore, its effect on Cdkn2a protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
CDKN2A mutant CDKN2A L62_E69del |
Transcript | NM_000077.5 |
gDNA | chr9:g.21971158_21971181del24 |
cDNA | c.185_208del24 |
Protein | p.L62_E69delLLLLHGAE |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_058195.4 | chr9:g.21971195_21994148del22954 | c.184_207del22954 | p.R62_G69delRRPGHDDG | RefSeq | GRCh38/hg38 |
XM_047422598.1 | chr9:g.21970999_21971022del24 | c.187_210del24 | p.P63_L70delPVDLAEEL | RefSeq | GRCh38/hg38 |
NM_001363763.2 | chr9:g.21970999_21971022del24 | c.187_210del24 | p.P63_L70delPVDLAEEL | RefSeq | GRCh38/hg38 |
NM_000077.4 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
NM_001195132 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
NM_000077.5 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69delLLLLHGAE | RefSeq | GRCh38/hg38 |
XM_011517676 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
XM_011517676.3 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69delLLLLHGAE | RefSeq | GRCh38/hg38 |
XM_011517676.2 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
NM_001195132.2 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69delLLLLHGAE | RefSeq | GRCh38/hg38 |
XM_047422597.1 | chr9:g.21970999_21971022del24 | c.187_210del24 | p.P63_L70delPVDLAEEL | RefSeq | GRCh38/hg38 |
NM_001195132.1 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
NM_058197.5 | chr9:g.21974621_21974644del24 | c.184_207del24 | p.G62_K69delGGRLWRTK | RefSeq | GRCh38/hg38 |
XM_011517675.3 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69delLLLLHGAE | RefSeq | GRCh38/hg38 |
XM_011517675.2 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
NM_000077 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
XM_011517675 | chr9:g.21971158_21971181del24 | c.185_208del24 | p.L62_E69del | RefSeq | GRCh38/hg38 |
XM_047422596.1 | chr9:g.21970999_21971022del24 | c.187_210del24 | p.P63_L70delPVDLAEEL | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
CDKN2A L62_E69del | unknown |