FGFR2 S372F
Gene Variant Detail

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Gene FGFR2
Variant S372F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 S372F lies within the extracellular domain of the Fgfr2 protein (Uniprot.org). S372F has been identified in sequencing studies (PMID: 27892470), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2025).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 S372F

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Transcript NM_000141.5
gDNA chr10:g.121515289G>A
cDNA c.1115C>T
Protein p.S372F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38
NM_001320658 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121515289G>A c.1115C>T p.S372F RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References