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Gene RAD51D
Variant S111T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions RAD51D S111T lies within the Walker A motif region of the Rad51d protein (PMID: 30836272). S111T retains the ability to interact with Xrcc2 and Rad51c in yeast assays, and restores mitomycin-induced DNA damage similar to wild-type Rad51d in cell culture (PMID: 16236763), and therefore, is predicted to have no effect on Rad51d protein function.
Associated Drug Resistance
Category Variants Paths

RAD51D mutant RAD51D S111T

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Transcript NM_002878.4
gDNA chr17:g.35107379C>G
cDNA c.332G>C
Protein p.S111T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002878 chr17:g.35107379C>G c.332G>C p.S111T RefSeq GRCh38/hg38
NM_002878.3 chr17:g.35107379C>G c.332G>C p.S111T RefSeq GRCh38/hg38
NM_002878.4 chr17:g.35107379C>G c.332G>C p.S111T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References