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JAK3 P307S - Gene Variant Detail

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Gene JAK3
Variant P307S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK3 P307S lies within the FERM domain of the Jak3 protein (UniProt.org). P307S has been identified in the scientific literature (PMID: 32639993), but has not been biochemically characterized and therefore, its effect on Jak3 protein function is unknown (PubMed, Dec 2024).
Associated Drug Resistance
Category Variants Paths

JAK3 mutant JAK3 P307S

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Transcript NM_000215.4
gDNA chr19:g.17841705G>A
cDNA c.919C>T
Protein p.P307S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000215.3 chr19:g.17841705G>A c.919C>T p.P307S RefSeq GRCh38/hg38
NM_000215.4 chr19:g.17841705G>A c.919C>T p.P307S RefSeq GRCh38/hg38
XM_047438786.1 chr19:g.17841705G>A c.919C>T p.P307S RefSeq GRCh38/hg38
NM_000215 chr19:g.17841705G>A c.919C>T p.P307S RefSeq GRCh38/hg38
XM_011527991.3 chr19:g.17841705G>A c.919C>T p.P307S RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References