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Gene ATR
Variant Y1404*
Impact List nonsense
Protein Effect loss of function - predicted
Gene Variant Descriptions ATR Y1404* results in a premature truncation of the Atr protein at amino acid 1404 of 2644 (UniProt.org). Due to the loss of the PI3K/PI4K domain and the FATC domain (UniProt.org), Y1404* is predicted to lead to a loss of Atr protein function.
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR inact mut ATR Y1404*

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Transcript NM_001184.4
gDNA chr3:g.142522782G>T
cDNA c.4212C>A
Protein p.Y1404*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.4 chr3:g.142522782G>T c.4212C>A p.Y1404* RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142522782G>T c.4212C>A p.Y1404* RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142522782G>T c.4212C>A p.Y1404* RefSeq GRCh38/hg38
NM_001184 chr3:g.142522782G>T c.4212C>A p.Y1404* RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries