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Gene TP53
Variant C242_R248delinsW
Impact List indel
Protein Effect unknown
Gene Variant Descriptions TP53 C242_R248delinsW results in a deletion of seven amino acids in the DNA-binding domain of the Tp53 protein from amino acids 242 to 248, combined with the insertion of a tryptophan (W) at the same site (UniProt.org). C242_R248delinsW has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon7 TP53 C242_R248delinsW

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Transcript NM_000546.6
gDNA chr17:g.7674221_7674238del18
cDNA c.726_743del18
Protein p.C242_R248delinsW
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126112.3 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_000546 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126114 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126113 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126112 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7674221_7674238del18 c.726_743del18 p.C242_R248delinsW RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries