TP53 T140_C141del
Gene Variant Detail

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Gene TP53
Variant T140_C141del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions TP53 T140_C141del results in the deletion of two amino acids in the DNA-binding domain of the Tp53 protein from amino acids 140 to 141 (PMID: 22713868). T140_C141del has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Sep 2025).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon5 TP53 T140_C141del

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Transcript NM_000546.6
gDNA chr17:g.7675189_7675194delGCAGGT
cDNA c.418_423delACCTGC
Protein p.T140_C141del
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.