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Gene | HRAS |
Variant | A134T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS A134T does not lie within any known functional domains of the Hras protein (UniProt.org). A134T has been identified in sequencing studies (PMID: 27149842), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS A134T |
Transcript | NM_005343.4 |
gDNA | chr11:g.533503C>T |
cDNA | c.400G>A |
Protein | p.A134T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001130442.2 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_001130442 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_005343.3 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_001130442.3 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_176795 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_005343 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
NM_176795.5 | chr11:g.533503C>T | c.400G>A | p.A134T | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
HRAS A134T | unknown |