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Gene | HRAS |
Variant | F82L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS F82L does not lie within any known functional domains of the Hras protein (UniProt.org). F82L has been identified in the scientific literature (PMID: 28939558, PMID: 25360634), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS F82L |
Transcript | NM_005343.4 |
gDNA | chr11:g.533812A>G |
cDNA | c.244T>C |
Protein | p.F82L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_005343.3 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_176795 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_001130442 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_005343 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_001130442.3 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_176795.5 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.533812A>G | c.244T>C | p.F82L | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
HRAS F82L | unknown |