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HRAS G13I - Gene Variant Detail

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Gene HRAS
Variant G13I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS G13I is hotspot mutation that lies within the GTP-binding region of the Hras protein (UniProt.org). G13I has been identified in the scientific literature (PMID: 26974156, PMID: 22817889), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2025).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS G13X HRAS G13I

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Transcript NM_005343.4
gDNA chr11:g.534285_534286delGGinsAT
cDNA c.37_38delGGinsAT
Protein p.G13I
Source Database RefSeq
Genome Build GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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