Gene Variant Detail

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Gene HRAS
Variant R123H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS R123H does not lie within any known functional domains of the Hras protein (UniProt.org). R123H has been identified in sequencing studies (PMID: 25303977, PMID: 36089135), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS R123H

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Transcript NM_005343.4
gDNA chr11:g.533535C>T
cDNA c.368G>A
Protein p.R123H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001130442.2 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_001130442 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_176795 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_176795.5 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_005343 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533535C>T c.368G>A p.R123H RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries