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Gene PIK3CA
Variant G12D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA G12D does not lie within any known functional domains of the Pik3ca protein (UniProt.org). G12D has been identified in sequencing studies (PMID: 23933559, PMID: 32947236), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA G12D

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Transcript NM_006218.4
gDNA chr3:g.179198860G>A
cDNA c.35G>A
Protein p.G12D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
XM_006713658 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
XM_011512894 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179198860G>A c.35G>A p.G12D RefSeq GRCh38/hg38

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries