Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene PIK3CA
Variant L113del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions PIK3CA L113del results in the deletion of an amino acid of the Pik3ca protein at amino acid 113 (UniProt.org). L113del has been identified in sequencing studies (PMID: 30138724, PMID: 31980592, PMID: 37465112), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA L113del

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_006218.4
gDNA chr3:g.179199162_179199164delCTC
cDNA c.337_339delCTC
Protein p.L113del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218.3 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
XM_006713658 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
NM_006218 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38
XM_011512894 chr3:g.179199162_179199164delCTC c.337_339delCTC p.L113del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References